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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| B6;129-Adora2atm1Dyj/J (Cat. No.: CEMM-07250187) | Inquiry | |
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These mice possess loxP sites on either side of exon 2 of the targeted Adora2a gene and may be useful in generating conditional mutations for studying locomoter activity response to addictive substances.
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| B6;129-Tmem259tm1.1Itl/J (Cat. No.: CEMM-07250310) | Inquiry | |
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These LoxP membralin mice possess loxP sites on either side of exons 2 through 4 of the ORF61 (open reading frame 61) gene and and have applications in studies related to spinal muscular atrophy and motor neuron diseases.
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| C57BL/6N-Tg(Slc32a1-icre/ERT2)3Gloss/J (Cat. No.: CEMM-07250311) | Inquiry | |
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These VGAT-iCreER transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Slc32a1 promoter region and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping throughout the brain in neurons that structurally resemble interneurons.
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| C57BL/6-Tg(Slc6a3-icre/ERT2)2Gloss/J (Cat. No.: CEMM-07250312) | Inquiry | |
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These DAT-iCreER transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Slc6a3 promoter region and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping of dopaminergic neurons in the substantia nigra and locus coeruleus, as well for studying drug addiction, Parkinson's disease and Attention Deficit-Hyperactivity Disorder (ADHD).
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| STOCK Tg(Tph2-icre/ERT2)6Gloss/J (Cat. No.: CEMM-07250313) | Inquiry | |
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These TPH2-iCreER transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Tph2 promoter and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping of Tph2 expressing neurons in the raphe nucleus.
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| STOCK Gabrg2tm2Lusc/J (Cat. No.: CEMM-07250314) | Inquiry | |
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These floxed mutant mice possess loxP sites flanking exon 8 of the Gabrg2 gene. This strain may be useful for generating conditional mutations for studying the role of gamma2 subunit of the GABA-A receptor in neurophysiology and major depression.
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| B6;129-Chattm1Jrs/J (Cat. No.: CEMM-07250322) | Inquiry | |
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These floxed mutant mice possess loxP sites flanking exons 3 and 4 of the Chat gene. This strain may be useful for generating conditional mutations for studying cholinergic neurotransmission and non-neuronal cholinergic systems.
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| B6;129S6-Gt(ROSA)26Sortm1(rtTA2S*M2)Whsu/J (Cat. No.: CEMM-07250332) | Inquiry | |
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This R26STOPrtTA mutant mouse strain combines two popular conditionally-regulated expression methodologies (Tet Expression and Cre Recombinase) providing a tool for doxycycline-inducible spatiotemporal and lineage specific expression of genes.
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| B6.Cg-Gt(ROSA)26Sortm1(CAG-GFP/Eif2c2)Zjh/J (Cat. No.: CEMM-07250357) | Inquiry | |
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R26-LSL-tAGO2 mice are used in the miRAP (miRNA tagging and Affinity Purification) method in conjunction with Cre recombinase expressing mice, for genetically targeted microRNA tagging and generating tissue specific miRNA expression profiles.
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| STOCK Nf1tm1Par/J (Cat. No.: CEMM-07250358) | Inquiry | |
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These Nf1flox mice possess loxP sites flanking exons 31-32 of the neurofibromatosis 1 gene (Nf1), and have applications in studying cancer, neural crest development and neurofibromatosis type I.
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For Research Use Only.