B6;129-Chattm1Jrs/J

Cat. No.: CEMM-07250322

Common Name: ChATflox
These floxed mutant mice possess loxP sites flanking exons 3 and 4 of the Chat gene. This strain may be useful for generating conditional mutations for studying cholinergic neurotransmission and non-neuronal cholinergic systems.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Chattm1Jrs
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Allele Name
targeted mutation 1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Chat
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Gene Name
choline acetyltransferase
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Chromosome
14
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MGI Accession ID show more close
Strain of Origin
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Molecular Note
Exons 3 and 4 were floxed and an FRT flanked neo inserted into intron 4 via homologous recombination.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, these mice can be bred as homozygotes.
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Breeding Strategy
Homozygote x Homozygote
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For Research Use Only.
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