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STOCK Gabrg2tm2Lusc/J
Cat. No.: CEMM-07250314
These floxed mutant mice possess loxP sites flanking exon 8 of the Gabrg2 gene. This strain may be useful for generating conditional mutations for studying the role of gamma2 subunit of the GABA-A receptor in neurophysiology and major depression.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gabrg2tm2Lusc
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Gabrg2
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| Gene Name |
gamma-aminobutyric acid (GABA) A receptor
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| Chromosome |
11
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| MGI Accession ID | show more close |
| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
Exon 8 was left flanked by single loxP sites after an FRT flanked neo cassette was excised via Flp-mediated recombination. A single flp site was left immediately downstream of the 3' loxP site.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
129X1/SvJ
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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For Research Use Only.
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