STOCK Sox11tm1.1Llei/J

Cat. No.: CEMM-07251021

Common Name: Sox11f
Sox11f/f mice have loxP sites flanking the only coding exon of the SRY (sex determining region Y)-box 11 (Sox11) gene. These mice may be useful when studying embryonic and adult neurogenesis.
Inquiry
Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Sox11tm1.1Llei
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Sox11
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Gene Name
SRY (sex determining region Y)-box 11
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Chromosome
12
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MGI Accession ID show more close
Strain of Origin
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Molecular Note
An FRT flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of the coding exon. An additional loxP site was inserted downstream of the coding exon. Flp-mediated recombination removed the neomycin resistance cassette and left the coding exon floxed.
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HUSBANDRY
Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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