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B6;129-Tor1atm3.1Wtd/J
Cat. No.: CEMM-07250579
Tor1aflox/flox mice possess loxP sites flanking exons 3-5 of the Tor1a gene, making this stain useful for studying DYT1 dystonia.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tor1atm3.1Wtd
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| Allele Name |
targeted mutation 3.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Tor1a
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| Gene Name |
torsin family 1
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| Chromosome |
2
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| MGI Accession ID | show more close |
| Strain of Origin |
(129S6/SvEvTac x C57BL/6J)F1
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| Molecular Note |
A targeting vector was designed to insert a loxP site upstream of exon 3 followed by a FRT flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 5 of the gene. Flpe-mediated recombination removed the FRT flanked neomycin cassette leaving exons 3-5 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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