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STOCK Syt12tm1.1Sud/J
Cat. No.: CEMM-07250300
Common Name: Syt12 S97A KI
This Syt12 (synaptotagmin XII) mutant strain combines an S97A amino acid mutation with loxP sites that enable cre-mediated elimination of tissue-specific expression. This strain may be useful in studies of neurotransmission and the presynaptic function of Syt12 phosphorylation.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Syt12tm1.1Sud
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| Allele Name |
targeted mutation 1.1
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| Gene Symbol |
Syt12
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| Gene Name |
synaptotagmin XII
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| Chromosome |
19
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
Serine 97 (exon 4) was mutated to alanine (S97A) and exons 4-6 were flanked by loxP sites in the targeting vector. An FRT flanked neomycin cassette was also incorporated. Flp-mediated recombination removed the neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintained as a live colony, heterozygotes may be bred.
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For Research Use Only.
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