STOCK Mirc28tm1Mtm/Mmjax

Cat. No.: CEMM-07250275

These microRNA cluster 28 (miR-296/miR-298) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Mirc28tm1Mtm
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Allele Name
targeted mutation 1
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Allele Attributes
Conditional ready (e.g. floxed); Reporter; Null/Knockout
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Gene Symbol
Mir296
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Gene Name
microRNA 296
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Chromosome
2
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Expressed Genes
lacZ, beta-galactosidase, E. coli
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MGI Accession ID show more close
Strain of Origin
129P2/OlaHsd
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Molecular Note
A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT lacZ-loxP-Neo-FRT loxP) upstream of the microRNA cluster stem loop and one loxP site immediately downstream of the microRNA stem loop.
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HUSBANDRY
Breeding Considerations
While maintaining a live colony, the donating investigator crossed heterozygote to wild-type. Homozygotes are viable, but fertility has not been assessed.
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For Research Use Only.
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