Online Inquiry
B6.Cg-Tg(CMV-AR*113Q)FMonk/J
Cat. No.: CEMM-07250733
Common Name: CMV-STOP-AR113Q
CMV-stop-AR113Q mice carry a loxP-flanked stop codon upstream of a human androgen receptor gene containing a polyglutamine expansion under the control of a cytomegalovirus promotor. This strain may be useful for generating conditional mutations in studies related to spinobulbar muscular atrophy (Kennedy disease).
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(CMV-AR*113Q)FMonk
show more
close
|
| Allele Name |
transgene insertion F
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); Inserted expressed sequence; Humanized sequence
show more
close
|
| Gene Symbol |
Tg(CMV-AR*113Q)FMonk
show more
close
|
| Gene Name |
transgene insertion F
show more
close
|
| Chromosome |
UN
show more
close
|
| Expressed Genes |
AR, androgen receptor, human
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x C3H)F2
show more
close
|
| Molecular Note |
The transgenic construct consists of CMV promoter sequences, a loxP-flanked neomycin-STOP cassette and a full length human androgen receptor (AR) cDNA containing a polyglutamine expansion with 113 repeats.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
show more
close
|
| Breeding Considerations |
While maintaining a live colony, these mice are bred as homozygotes. The donating investigator indicates that the transgene may have inserted on the X chromosome.
show more
close
|
For Research Use Only.
Related Products