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B6.129P2(Cg)-Trim3tm1.1Kstrn/J
Cat. No.: CEMM-07250966
Common Name: Trim3lox
Trim3lox mice possess loxP sites flanking exons 3-5 of the tripartite motif-containing 3 (Trim3) gene. These floxed mice are useful when studying actin cytoskeletal regulation of synaptic function and neuronal trafficking.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Trim3tm1.1Kstrn
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Trim3
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| Gene Name |
tripartite motif-containing 3
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| Chromosome |
7
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| MGI Accession ID | show more close |
| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
An FRT flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exons 3 through 5 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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