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STOCK Cbfbtm2.1Ddg/J
Cat. No.: CEMM-07250675
Common Name: Cbfbf
Exons 1 and 2 of the mouse Cbfb gene are flanked by loxP sites in this conditional mutant strain. Cre-mediated excision of the floxed region in the Cbfbf mice results in a knockout allele.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Cbfbtm2.1Ddg
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Cbfb
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| Gene Name |
core binding factor beta
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| Chromosome |
8
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
An FRT flanked neomycin cassette and loxP site were introduced 1 kb upstream of the transcription start site, and a second loxP site was place in intron 2. Flp-mediated recombination removed the FRT flanked neo cassette.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
Heterozygous and homozygous floxed mice are viable and fertile.
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For Research Use Only.
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