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B6.129S4(SJL)-Crhr2tm1.1(cre)Lbrl/J
Cat. No.: CEMM-07250960
Common Name: Crhr2-ires-Cre
Crhr2-ires-Cre knock-in mice express Cre recombinase under the direction of the Crhr2 promoter in nodose ganglia of vagal sensory neurons.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Crhr2tm1.1(cre)Lbrl
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Crhr2
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| Gene Name |
corticotropin releasing hormone receptor 2
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
129S4/SvJae
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| Molecular Note |
A targeting construct was designed to insert an internal ribosomal entry site (IRES) and a Cre Recombinase with a polyadenylation signal, followed by a FRT flanked neomycin resistance (neo) cassette, downstream of the stop codon of the corticotropin releasing hormone receptor 2 (Crhr2) gene. The neomycin resistance gene was subsequentlyremoved by crossing with Act-Flpe mice.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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