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STOCK Mirc26tm1Mtm/Mmjax
Cat. No.: CEMM-07250263
These microRNA cluster 26 (miR-30b/miR-30d) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is widespread. This mutant mouse strain may be useful in studies of microRNA biology.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Mirc26tm1Mtm
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; Null/Knockout
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| Gene Symbol |
Mir30b
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| Gene Name |
microRNA 30b
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| Chromosome |
15
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| Expressed Genes |
lacZ, beta-galactosidase, E. coli
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| MGI Accession ID | show more close |
| Site of Expression |
Ubiquitous at E11.5
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| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT lacZ-loxP-Neo-FRT loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA cluster stem loop.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
While maintaining a live colony, these mice have been bred as heterozygotes. The Donating Investigator does not maintain this as a homozygous colony.
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For Research Use Only.
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