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    Mouse Models

    Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.

    For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.

    • Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
    • Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
    • Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
    • Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.

    If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.

    Our Mouse Models

    Reporter Mouse
    Floxed Mouse
    Recombinase-expressing Mouse
    Inducible Mouse
    B6;129S-Grptm1.1Zfc/J (Cat. No.: CEMM-07250956) Inquiry
    GrpF mice possess loxP sites flanking exon 1 of the gastrin releasing peptide (Grp) gene. These floxed mice are useful when studying non-histaminergic scratching behavior.
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    STOCK Mtss1tm1.1Oro/J (Cat. No.: CEMM-07250962) Inquiry
    MIMEX15 mice possess loxP sites flanking exon 15 of the MTSS I-BAR domain containing 1 (Mtss1) gene. Exon 15 encodes that Cortactin/Src-interacting domain of MTSS1. These floxed mice are useful when studying actin cytoskeletal regulation of synaptic function and neurodegeneration.
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    B6.Cg-Ackr3tm1Fma/J (Cat. No.: CEMM-07250963) Inquiry
    Cxcr7lox/lox mice possess loxP sites flanking exon 2 of the atypical chemokine receptor 3 (Ackr3) gene. This strain may be useful in immunological studies as well as studies of cardiac development and cancer.
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    B6.129P2(Cg)-Trim3tm1.1Kstrn/J (Cat. No.: CEMM-07250966) Inquiry
    Trim3lox mice possess loxP sites flanking exons 3-5 of the tripartite motif-containing 3 (Trim3) gene. These floxed mice are useful when studying actin cytoskeletal regulation of synaptic function and neuronal trafficking.
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    B6(SJL)-Dusp16tm1c(EUCOMM)Wtsi/FrdlJ (Cat. No.: CEMM-07250970) Inquiry
    Dusp16 floxed mice have loxP sites flanking exon 3 of the dual specificity phosphatase 16 (Dusp16) gene. These mice are useful for studying neural progenitor proliferation during embryonic and adult neurogenesis.
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    B6;C-Nrn1tm1.1Ndiv/J (Cat. No.: CEMM-07250972) Inquiry
    Cpg15flox mice possess loxP sites flanking exons 2-3, encoding the entire coding sequence of the neuritin 1 (Nrn1) gene. These floxed mice are useful when studying the development and growth of differentiating neurons.
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    B6.Cg-Galtm1.1Pjen/J (Cat. No.: CEMM-07250984) Inquiry
    GalcKO mice have loxP sites flanking exon 3 of the galanin and GMAP prepropeptide (Gal) gene. These mice are useful for studying the role of galanin in coping behaviors.
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    B6(Cg)-Slc17a8em1(cre/ERT2)Zyliu/J (Cat. No.: CEMM-07250994) Inquiry
    vGlut3-P2A-iCreERT2 mice carry a CRISPR/Cas9 generated insertion of a P2A-iCre/ERT2 cassette in exon 12, immediately before the stop codon of the Slc17a8 gene, without disrupting endogenous vesicular glutamate transporter 3 expression. These mice may be used to generate tamoxifen-induced conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic synaptic vesicle trafficking.
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    B6(Cg)-Ndnftm1.1(cre/ERT2)Ispgl/J (Cat. No.: CEMM-07251004) Inquiry
    Ndnf-IRES-CreERT2 knock-in mice have a cre/ERT2 fusion gene inserted into the 3' UTR in exon 4 of the neuron-derived neurotrophic factor (Ndnf) gene. These mice retain endogenous Ndnf expression and may be used to generate conditional mutations for studying gain-or-loss of function, fate mapping and/or circuit dissection of NDNF+ cell populations.
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    B6.129S6(SJL)-Zfhx3tm1.1Jtd/J (Cat. No.: CEMM-07251013) Inquiry
    Atbf1flox/flox mice have loxP sites flanking exons 7-8 of the zinc finger homeobox 3 (Zfhx3), encoding most of the zinc finger motifs and all four homeodomains. These mice may be useful when studying neuronal differentiation and tumorigenesis (e.g., prostate cancer, breast cancer).
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    For Research Use Only.