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B6.129S6(SJL)-Zfhx3tm1.1Jtd/J
Cat. No.: CEMM-07251013
Common Name: Atbf1flox
Atbf1flox/flox mice have loxP sites flanking exons 7-8 of the zinc finger homeobox 3 (Zfhx3), encoding most of the zinc finger motifs and all four homeodomains. These mice may be useful when studying neuronal differentiation and tumorigenesis (e.g., prostate cancer, breast cancer).
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Zfhx3tm1.1Jtd
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Zfhx3
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| Gene Name |
zinc finger homeobox 3
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| Chromosome |
8
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
A loxP site was inserted upstream of exon 7. A FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette and left exons 7 and 8 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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