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B6;129S-Grptm1.1Zfc/J
Cat. No.: CEMM-07250956
Common Name: GrpF
GrpF mice possess loxP sites flanking exon 1 of the gastrin releasing peptide (Grp) gene. These floxed mice are useful when studying non-histaminergic scratching behavior.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Grptm1.1Zfc
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Grp
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| Gene Name |
gastrin releasing peptide
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| Chromosome |
18
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| MGI Accession ID | show more close |
| Strain of Origin |
129S7/SvEvBrd-Hprt+
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| Molecular Note |
The targeting vector is designed to insert a loxP site upstream of exon 1, and an FRT flanked neomycin selection cassette followed by a second loxP site downstream of exon 1 of the gene. Flp-mediated recombination removed the FRT flanked neo cassette leaving exon 1 floxed.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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