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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| B6;CBA-Tg(Emx1-cre/ERT2)1Kess/SshiJ (Cat. No.: CEMM-07250642) | Inquiry | |
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Emx1-Cre-ERT2 mice express Cre in pallial precursors cells making them useful for applications requiring tamoxifen-induced deletion of floxed sequences in these cells.
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| C.129S(B6)-Chrna3tm1.1Hwrt/J (Cat. No.: CEMM-07250231) | Inquiry | |
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These α3[5] mice contain a mutation designed to introduce 5 nucleotide mutations to exon 5 of mouse nicotinic acetylcholine receptor (nAChR) neuronal α3 subunit and a loxP-flanked neomycin (neo) resistance cassette upstream of exon 5. These mice may be useful for studying the pathological mechanisms of receptor assembly and trafficking in neurological and psychiatric disorders including Alzheimer's disease, Parkinson's disease, schizophrenia, and epilepsy, as well as drug addiction, response to pain, and nicotine induced behaviors.
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| STOCK Pax3tm1.1(cre/ERT2)Lepr/J (Cat. No.: CEMM-07250572) | Inquiry | |
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These mice express tamoxifen-inducible Cre recombinase under the direction of the Pax3 promoter in.
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| STOCK Egr2tm2(cre)Pch/J (Cat. No.: CEMM-07250574) | Inquiry | |
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Krox-20cre mice express Cre recombinase under the direction of the Egr2 promoter in the hindbrain, Schwann cells, and long bones.
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| STOCK Kiss1tm1.1(cre/EGFP)Stei/J (Cat. No.: CEMM-07250362) | Inquiry | |
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The Kiss1-CreGFP allele expresses a CreGFP fusion protein from the Kiss1 promoter/enhancer elements. These knock-in mice may be useful for visualizing KISS1 secreting neurons and for studying their role in fertility.
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| B6.129S(SJL)-Cyp19a1tm2.1(cre)Shah/J (Cat. No.: CEMM-07250628) | Inquiry | |
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aroCre mice express Cre recombinase in portions of the amygdala. They may be useful in applications examining sexually dimorphic social behaviors.
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| STOCK Gpr65tm1.1(cre)Lbrl/RcngJ (Cat. No.: CEMM-07250721) | Inquiry | |
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Gpr65-ires-Cre knock-in mice express Cre recombinase under the direction of the Gpr65 promoter in vagal sensory neurons in the gastrointestinal tract that respond to ingested nutrients.
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| STOCK Glp1rtm1.1(cre)Lbrl/RcngJ (Cat. No.: CEMM-07250722) | Inquiry | |
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Glp1r-ires-Cre knock-in mice express Cre recombinase under the direction of the Glp1r promoter in vagal sensory neurons in the gastrointestinal tract that respond to gastric and intestinal distension.
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| STOCK P2ry1tm1.1(cre)Lbrl/RcngJ (Cat. No.: CEMM-07250723) | Inquiry | |
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P2ry1-ires-Cre knock-in mice express Cre recombinase under the direction of the P2ry1 promoter in vagal sensory neurons in the lung and brain stem that control respiration.
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| B6(C3)-Agtr1atm1.1(cre)Ekrs/J (Cat. No.: CEMM-07250814) | Inquiry | |
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AT1aR-Cre mice express Cre recombinase and zsGreen under the direction of the Agtr1a promoter and may be useful when studying the regulation of stress responses.
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For Research Use Only.