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STOCK Glp1rtm1.1(cre)Lbrl/RcngJ
Cat. No.: CEMM-07250722
Common Name: Glp1r-ires-Cre
Glp1r-ires-Cre knock-in mice express Cre recombinase under the direction of the Glp1r promoter in vagal sensory neurons in the gastrointestinal tract that respond to gastric and intestinal distension.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Glp1rtm1.1(cre)Lbrl
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Glp1r
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| Gene Name |
glucagon-like peptide 1 receptor
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| Chromosome |
17
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Glp1r encodes a receptor present on many cell types including pancreatic Β cells, subsets of neurons in the central nervous system, as well as a subset of vagal sensory neurons that project to the gastrointestinal tract.
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| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
A cassette encoding IRES, Cre recombinase, and an FRT flanked neomycin selection cassette is inserted into the mouse Glp1r locus 3 base pairs downstream of the coding sequence stop codon.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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