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STOCK Pax3tm1.1(cre/ERT2)Lepr/J
Cat. No.: CEMM-07250572
Common Name: Pax3CE
These mice express tamoxifen-inducible Cre recombinase under the direction of the Pax3 promoter in.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Pax3tm1.1(cre/ERT2)Lepr
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Recombinase-expressing; Inducible; Null/Knockout
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| Gene Symbol |
Pax3
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| Gene Name |
paired box 3
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| Chromosome |
1
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| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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| MGI Accession ID | show more close |
| Site of Expression |
Cre-ERT2 fusion protein is expressed from endogenous Pax3 promoter/enhancer elements during the development of myogenic and neural crest progenitors.
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| Strain of Origin |
C57BL/6 x 129
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| Molecular Note |
A rabbit beta-globin intron, Cre/ERT2 fusion gene, SV40 late polyadenylation signal and FRT flanked neomycin cassette replaced the coding sequence in exon 1. Flp-mediated recombination removed the selection cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
When maintaining a live colony heterozygous mice may be bred to wildtype mice from the colony. The donating investigator has not attempted to make this strain homozygous.
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For Research Use Only.
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