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STOCK Egr2tm2(cre)Pch/J
Cat. No.: CEMM-07250574
Common Name: KCN
Krox-20cre mice express Cre recombinase under the direction of the Egr2 promoter in the hindbrain, Schwann cells, and long bones.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Egr2tm2(cre)Pch
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Egr2
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| Gene Name |
early growth response 2
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| Chromosome |
10
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre recombinase is exprssed in the hindbrain, Schwann cells, and long bones.
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| Strain of Origin |
129S2/SvPas
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| Molecular Note |
DNA sequences corresponding to the two alternative initiation codons were replaced by an nls-Cre gene, followed by a neomycin cassette. Expression was expected in the hindbrain, bones and the peripheral nervous system as well as both the male and female germlines.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
When maintaining a live colony heterozygous mice may be bred to wildtype mice from the colony. The donating investigator reports that homozygotes die soon after birth.
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For Research Use Only.
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