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B6;CBA-Tg(Emx1-cre/ERT2)1Kess/SshiJ
Cat. No.: CEMM-07250642
Common Name: Emx1-CreERT2
Emx1-Cre-ERT2 mice express Cre in pallial precursors cells making them useful for applications requiring tamoxifen-induced deletion of floxed sequences in these cells.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Emx1-cre/ERT2)1Kess
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Tg(Emx1-cre/ERT2)1Kess
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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| MGI Accession ID | show more close |
| Site of Expression |
Cre-ERT2 fusion protein is expressed from endogenous Emx1 promoter/enhancer elements in the developing brain.
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| Strain of Origin |
(C57BL/6 x CBA)F1
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| Molecular Note |
A P1 artificial chromosome was Created that contained a tamoxifen-inducible Cre recombinase with a nuclear localization signal fused to the initiation codon. Expression recapitulates endogenous expression in the cortical precursors.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6CBAF1/J
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| Breeding Considerations |
When maintaining a live colony hemizygous mice may be bred to wildtype (non-carrier) mice from the colony or to C57BL/6J. The donating investigator has not attempted to make this strain homozygous.
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| Breeding Strategy |
Noncarrier x Hemizygote; Hemizygote x Noncarrier
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For Research Use Only.
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