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C57BL/6-Pgbd5tm1.1Aken/J
Cat. No.: CEMM-07251115
Common Name: Pgbd5-floxed
Pgbd5-floxed mice possess loxP sites flanking exon 4 of the piggyBac transposable element derived 5 (Pgbd5) gene. These mice may be useful for studying the role of Pgbd5 in neuronal development and plasticity as well as genomic rearrangements and instability in various cancers.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Pgbd5tm1.1Aken
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Pgbd5
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| Gene Name |
piggyBac transposable element derived 5
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| Chromosome |
8
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6NTac
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| Molecular Note |
The targeting cassette is composed of an FRT site, lacZ sequence, a loxP site, a neomycin resistance gene, a second FRT site, and a second loxP site inserted upstream of exon 4. A third loxP site is inserted downstream of exon 4. FLP-mediated recombination removed the lacZ and neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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