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B6;129-Dvl2tm1.1Wds/J
Cat. No.: CEMM-07250713
Common Name: Dvl2flox
These floxed mutant mice possess loxP sites flanking exons 2-14 of the Dvl2 gene. This strain may be useful for generating conditional mutations in studies of neurodevelopment and planar cell polarity.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Dvl2tm1.1Wds
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Dvl2
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| Gene Name |
dishevelled segment polarity protein 2
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| Chromosome |
11
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| MGI Accession ID | show more close |
| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
An FRT flanked neo cassette and loxP site were inserted upstream of exon 2 and a loxP site was inserted into exon 15 distal to the stop codon. Flp mediated recombination removed the neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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