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B6;129P2-Gt(ROSA)26Sortm1Mom/MomJ
Cat. No.: CEMM-07250059
Common Name: ROSA-STOP-taulacZ
This targeted insertion of a loxP-flanked STOP taulacZ cassette into the Gt(ROSA)26Sor locus provides a reporter allele for Cre recombinase expression in which taulacZ is expressed along the axons of neurons in which Cre recombinase has excised the loxP-flanked STOP.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm1Mom
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
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| Gene Symbol |
Gt(ROSA)26Sor
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| Gene Name |
gene trap ROSA 26
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| Chromosome |
6
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| Expressed Genes |
lacZ, beta-galactosidase, E. coli
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| MGI Accession ID | show more close |
| Site of Expression |
When bred with mice containing Cre recombinase, LacZ will be expressed in Cre-expressing cells of the offspring.
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| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
A splice acceptor containing Asc1 (CTAGTTCCCTTTTTTTTCACAG-GTTGGCGCGCCACGGTGATC) was inserted in the Nhe site of the intron of Gt(ROSA)26Sor, and then, into the Asc1 site, a sequence containing Asc1-loxP-CAT-pA-loxP-tauLacZ-betaGlobinpA-FRT Neo-FRT Asc1 was inserted to generate this allele with a loxP-flanked STOP sequence just upstream of tauLacZ.
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For Research Use Only.
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