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129S.B6(SJL)-Fgf13tm1c(EUCOMM)Wtsi/GolJ
Cat. No.: CEMM-07251050
Common Name: Fhf2fl
Fhf2fl/fl floxed mice have loxP sites flanking exon 3 of the X-linked fibroblast growth factor 13 (Fgf13) gene. These mice are useful for studying the effects of sodium channel inactivation on cardiac conduction failure.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Fgf13tm1c(EUCOMM)Wtsi
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| Allele Name |
targeted mutation 1c
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Fgf13
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| Gene Name |
fibroblast growth factor 13
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| Chromosome |
X
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6N-Atm1Brd
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| Molecular Note |
FLP-mediated recombination removed the lacZ and neomycin cassette from Fgf13tm1a(EUCOMM)Wtsi.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
129S1/SvImJ
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| Breeding Considerations |
When maintaining a live colony, homozygous females may be bred to hemizygous males. The donating investigator reports that after cre recombination, the resulting Fhf2KO mice are not viable on a C57BL/6 genetic background.
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| Breeding Strategy |
Heterozygote x Hemizygote
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For Research Use Only.
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