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C57BL/6J-Fcer1gem1Gfng/J
Cat. No.: CEMM-07251064
Common Name: Fcer1g loxP
Genetic Background: C57BL/6J
Fcer1g floxed mice have loxP sites flanking exons 2-3 of the Fc receptor, IgE, high affinity I, gamma polypeptide gene, which encodes the transmembrane domain. Exposure to Cre recombinase removes the floxed sequence - creating a null allele. These Fcer1g floxed mice may be useful in studying microglial expression and function.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Fcer1gem1Gfng
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Fcer1g
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| Gene Name |
Fc receptor
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
CRISPR/Cas9 genome editing is used to insert loxP sites flanking exons 2 and 3 (encoding the transmembrane domain).
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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