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B6.129(Cg)-Dag1tm2.1Kcam/J
Cat. No.: CEMM-07250176
These mice possess loxP sites on either side of exon 2 of the Dag1 (dystroglycan 1) gene. When bred to mice with a cre recombinase gene under the control of a promoter of interest, exon 2 of the targeted gene is deleted in the tissue of interest.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Dag1tm2.1Kcam
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Dag1
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| Gene Name |
dystroglycan 1
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| Chromosome |
9
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A targeting vector was used to introduce a loxP site downstream of exon 2 and insert a floxed neo cassette in the upstream intron. Cre mediated recombination removed the neomycin cassette, leaving a loxP site in intron 1 and another 3' to the 3' UTR.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintained as a live colony, homozygotes may be bred.
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For Research Use Only.
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