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B6(C)-Tg(CAG-mCherry, -GAL4)774Gsn/J
Cat. No.: CEMM-07250339
These transgenic mice carry both an mCherry fluorescent gene flanked by loxP sites and the yeast transcription activator protein GAL4 under the control of a cytomegalovirus enhancer/beta actin promoter (CAG). This strain may be effectively used as a component of the GAL4-UAS (Upstream Activation Sequence) system to activate gene transcription.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(CAG-mCherry,-GAL4)774Gsn
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| Allele Name |
transgene insertion 774
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| Allele Attributes |
Inserted expressed sequence
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| Gene Symbol |
Tg(CAG-mCherry,-GAL4)774Gsn
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| Gene Name |
transgene insertion 774
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| Chromosome |
UN
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| Expressed Genes |
GAL4, transcriptional activator GAL4, yeast; RFP, Red Fluorescent Protein, coral
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| MGI Accession ID | show more close |
| Site of Expression |
These mice express mCherry, but not GAL4 in the absence of Cre. When crossed with a Cre strain, mCherry is excised and GAL4 can be expressed in tissues of interest.
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| Strain of Origin |
C57BL/6 x BALB/c
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| Molecular Note |
A 1.7 kb cytomegalovirus (CMV) early enhancer element/chicken beta-actin (CAG) promoter drives expression of a loxP-flanked mCherry fluorescent gene (0.7 kb) and a 2.9 kb yeast transcription activator GAL4 open ready frame.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Noncarrier
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| Breeding Considerations |
When maintaining the live colony, hemizygous mice may be bred with wildtype (non-carrier) mice from the colony or with C57BL/6J inbred mice. Homozygous viability/fertility were not determined by the donating laboratory.
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For Research Use Only.
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