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129S6.FVB(B6)-Tg(Drd1a-cre)AGsc/KndlJ
Cat. No.: CEMM-07250659
Common Name: D1-Cre
Cre is expressed from the mouse Drd1a promoter in this YAC transgenic strain (D1-Cre). The spatio-temporal pattern of Cre expression in dopaminoceptive neurons is reported to closely recapitulate that of the endogenous Drd1a gene in embryonic and adult stages.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Drd1a-cre)AGsc
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| Allele Name |
transgene insertion A
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Drd1a-cre)AGsc
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| Gene Name |
transgene insertion A
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| Chromosome |
UN
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| Expressed Genes |
Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre is expressed in dopaminoceptive neurons.
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| Strain of Origin |
FVB/N
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| Molecular Note |
A YAC containing the Cre open reading frame with a nuclear localization signal and under the control of a Drd1a promoter was used to Create a transgene. Expression was confirmed through crosses with three reporter lines and localized to the major dopaminoceptive regions. Line A contains 3 copies of the transgene.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Noncarrier
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| Breeding Considerations |
Hemizygotes are viable and fertile.
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| Breeding Strategy |
Noncarrier x Hemizygote; Hemizygote x Noncarrier
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For Research Use Only.
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