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STOCK Tg(Rr5-GFP/cre)1Sapc/J
Cat. No.: CEMM-07250223
Hoxb4-ENE-GFPCre transgenic mice have expression of a GFP/Cre fusion protein directed primarily to developing spinal cord and hindbrain by the mouse homeobox B4 early neuronal enhancer (ENE) region and heat shock protein 1B minimal promoter. These Hoxb4-ENE-GFPCre transgenic mice may be useful as a Cre-lox or fluorescent tool for the fate-mapping/lineage-tracing of Hoxb4-expressing neurons in the developing neural tube.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Rr5-GFP/cre)1Sapc
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Tg(Rr5-GFP/cre)1Sapc
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
GFP, Green Fluorescent Protein; Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Expression of a GFP/Cre fusion protein is directed primarily to developing spinal cord and hindbrain.
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| Strain of Origin |
FVB/NJ
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| Molecular Note |
The early neuronal Hoxb4 enhancers with an Hspa1b minimal promoter were used to drive expression of a GFP/Cre fusion gene in neural tissue including the neural tube up to the r6/r7 boundary, the dorsal root ganglia, the trigeminal (Vth) cranial nerve, and Xth cranial nerve. No line information was given.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Noncarrier
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| Breeding Considerations |
When maintaining a live colony, transgenic carrier mice may be bred to wildtype (non-carrier) mice from the colony.
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For Research Use Only.
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