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B6.129(Cg)-Cacna2d1tm1.1Gfng/J
Cat. No.: CEMM-07250820
Common Name: Cavα2δ1 flox
These Cavα2δ1 floxed mutant mice possess loxP sites flanking exon 6 of the Cacna2d1 gene. This strain may be useful for generating conditional mutations in applications related to nociception and peripheral nerve injury.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Cacna2d1tm1.1Gfng
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Cacna2d1
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| Gene Name |
calcium channel
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| Chromosome |
5
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
An FRT flanked neomycin selection cassette and a loxP site was inserted downstream of exon 6 of the targeted gene another loxP site was inserted upstream of exon 6. Flp-mediated recombination removed the FRT flanked neo cassette leaving exon 6 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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