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STOCK Tg(Htr6-cre/ERT2)NIDA108Htz/J
Cat. No.: CEMM-07250800
Common Name: Htr6-CreERT2
These transgenic BAC mice express tamoxifen-inducible cre-ERT2 from the mouse Htr6 promoter. Expression occurs in Htr6-expressing cells, including a subclass of excitatory interneurons in the dorsal horn of the spinal cord.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Htr6-cre/ERT2)NIDA108Htz
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| Allele Name |
transgene insertion NIDA108
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Tg(Htr6-cre/ERT2)NIDA108Htz
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| Gene Name |
transgene insertion NIDA108
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| Chromosome |
UN
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| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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| MGI Accession ID | show more close |
| Site of Expression |
When crossed with mice carrying loxP-flanked sequences of interest, Tamoxifen inducuble Cre is expressed in Htr6-expressing cells, including a subclass of excitatory interneurons in the dorsal horn of the spinal cord.
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| Strain of Origin |
C57BL/6J
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| Molecular Note |
Expression of tamoxifen-inducible Cre-ERT2 is driven from the mouse Htr6 promoter contained on BAC RP23-65B16. This BAC encodes 4 additional genes: Rnf186, Tmco4, Nbl1 and Minos1. The modified BAC vector was introduced to C57BL/6J embryos.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Noncarrier
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| Breeding Considerations |
Hemizygotes are viable and fertile.
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| Breeding Strategy |
Hemizygote x Noncarrier; Noncarrier x Hemizygote
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| Coat Color |
Mice from this strain can be either black or agouti.
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For Research Use Only.
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