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B6J.129S-Slc6a12tm1.1Ncd/J
Cat. No.: CEMM-07250776
Common Name: BGT1-flox
BGT1-flox mice possess loxP sites flanking exons 3-5 of the solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 gene. This strain may be useful for studying the role of BGT1 in the brain and liver.
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Status | Live Mouse Frozen Embryo |
Age | 4 weeks 12 weeks Customized Age |
Sex | Male Female |
GENETICS | |
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Allele Symbol |
Slc6a12tm1.1Ncd
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Allele Name |
targeted mutation 1.1
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Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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Gene Symbol |
Slc6a12
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Gene Name |
solute carrier family 6 (neurotransmitter transporter
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Chromosome |
6
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MGI Accession ID | show more close |
Strain of Origin |
(129S6/SvEvTac x C57BL/6J)F1
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Molecular Note |
A loxP site was inserted upstream to exon 3. A FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neo cassette and left exons 3 through 5 floxed.
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HUSBANDRY | |
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Suggested Controls |
C57BL/6J Wild-type from the colony
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Breeding Considerations |
When maintaining a live colony, mice homozygous for the floxed allele may be bred together.
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Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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