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B6.129S2(FVB)-Pak4tm2.1Amin/J
Cat. No.: CEMM-07250295
This Pak4-floxed strain may be useful for studying the role of Pak4 in the development of extraembryonic tissue, embryonic vasculature, and the placenta.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Pak4tm2.1Amin
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Pak4
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| Gene Name |
p21 (RAC1) activated kinase 4
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| Chromosome |
7
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| MGI Accession ID | show more close |
| Strain of Origin |
129S2/SvPas
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| Molecular Note |
A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 4. Germ line, Cre mediated recombination removed the neo cassette leaving exons 2 through 4 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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