STOCK Pomt2tm1.1Hhu/J

Cat. No.: CEMM-07250368

These floxed-POMT2 mice may be useful for studying central nervous system malformations such as Walker-Warburg syndrome and muscle-eye-brain disease.
Inquiry
Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Pomt2tm1.1Hhu
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Allele Name
targeted mutation 1.1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Pomt2
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Gene Name
protein-O-mannosyltransferase 2
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Chromosome
12
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MGI Accession ID show more close
Strain of Origin
(129S6/SvEvTac x C57BL/6J)F1
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Molecular Note
An FRT flanked neo cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 2 through 4 floxed.
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HUSBANDRY
Suggested Controls
Wild-type from the colony
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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