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C57BL/6J-Grin2bem5Lutzy/J
Cat. No.: CEMM-07250925
Common Name: Grin2b flox
This Grin2bflox CRISPR/Cas9 generated mutant of the Grin2b gene possesses loxP sites flanking 599 nucleotides (exon 4 of Ensembl transcript 201 and exon 5 of transcript 202). This strain may be useful for generating conditional mutations in applications related to neurodevelopment.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Grin2bem5Lutzy
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| Allele Name |
endonuclease-mediated mutation 5
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Grin2b
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| Gene Name |
glutamate receptor
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
CRISPR/Cas9 genome editing is used to insert loxP sequences flanking the second coding exon of Grin2b (exon 4 of Ensembl Grin2b transcript 201/ exon 5 of Ensembl transcript 202).
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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