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STOCK Lmnatm1.1Yxz/J
Cat. No.: CEMM-07250595
Common Name: Lmnaflox
Lmnaflox/flox mice possess loxP sites flanking exon 2 of the lamin A gene, making them useful for studying the role of Lamin-A in specific cell types, and its influence on the progression of human diseases.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Lmnatm1.1Yxz
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Lmna
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| Gene Name |
lamin A
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| Chromosome |
3
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S4/SvJae)F1
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| Molecular Note |
A loxP site was inserted upstream of exon 2. An FRT flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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