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B6(SJL)-Prdm16tm1.1Snok/J
Cat. No.: CEMM-07250906
Common Name: PRDM16fl
Prdm16fl/fl mice possess loxP sites flanking exons 6-7 of the PR domain containing 16 (Prdm16) gene. These floxed mice are useful for tissue specific deletion of Prdm16 when studying hematopoiesis and inflammatory gene expression in leukemia.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Prdm16tm1.1Snok
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Prdm16
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| Gene Name |
PR domain containing 16
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| Chromosome |
4
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6NTac
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| Molecular Note |
THe targeting construct is designed to insert an FRT flanked neomycin selection cassette, followed by a loxP site, upstream of exon 6, and a second loxP site downstream of exon 7 of the gene. Flp-mediated recombination removed the FRT flanked neo cassette leaving exons 6 and 7 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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