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STOCK Islr2tm2.1Ddg/J
Cat. No.: CEMM-07250569
A portion of exon 3 of the mouse Islr2 (Linx) gene is flanked by loxP sites in this targeted mutant strain. Cre excision of the floxed region results in a knockout of the gene.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Islr2tm2.1Ddg
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Islr2
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| Gene Name |
immunoglobulin superfamily containing leucine-rich repeat 2
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| Chromosome |
9
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
A loxP site was introduced to intron 2 and a FRT PGK-Neo-pA-FRT loxP cassette was introduced to exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Homozygous and heterozygous floxed mice are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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