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STOCK Gt(ROSA)26Sortm1.1(CAG-EGFP)Fsh/Mmjax
Cat. No.: CEMM-07250197
These RCE:loxP mice harbor the R26R CAG-boosted EGFP (RCE) reporter allele with a loxP-flanked STOP cassette upstream of the enhanced green fluorescent protein (EGFP) gene. After removal of the loxP-flanked STOP cassette by cre-mediated recombination, EGFP reporter expression is directed to the cells/tissues dependent upon expression pattern of the promoter driving Cre recombinase.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm1.1(CAG-EGFP)Fsh
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
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| Gene Symbol |
Gt(ROSA)26Sor
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| Gene Name |
gene trap ROSA 26
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| Chromosome |
6
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| Expressed Genes |
GFP, Green Fluorescent Protein
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| MGI Accession ID | show more close |
| Site of Expression |
EGFP will be expressed in cells where promoters driving Cre recombinase are expressed.
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| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
The CAG promoter drives expression of EGFP preceded by a floxed neo and STOP cassette and a second FRT flanked STOP cassette. In this allele, germ line, flp mediated recombination removes the second STOP cassette leaving a single FRT site. Removal of the first neo/STOP cassette is required to achieve EGFP expression.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, heterozygous mice may be bred together or to wildtype mice from the colony. Homozygous mice may also be bred together.
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For Research Use Only.
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