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STOCK Gata4tm2(Gata4)Wtp/Mmjax
Cat. No.: CEMM-07250266
These knock-in mutant mice possess a floxed GATA4 cDNA with a transcriptional stop cassette followed by an alkaline phosphatase cDNA; cre-mediated excision activates AP expression. This mutant mouse strain may be useful in studies of cell lineage tracing in the developing and adult heart.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gata4tm2(Gata4)Wtp
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Reporter; Inserted expressed sequence
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| Gene Symbol |
Gata4
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| Gene Name |
GATA binding protein 4
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| Chromosome |
14
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| Expressed Genes |
Gata4, GATA binding protein 4, mouse, laboratory
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
Exon 2 was replaced with a floxed full-length Gata4 cDNA with a transcription STOP sequence followed by an alkaline phosphatase gene with a 3' FRT site. An FRT flanked neo cassette used for selection purposes was removed by germ line, flp-mediated recombination. Cre mediated recombination is necessary to activate alkaline phospatase expression.
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For Research Use Only.
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