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B6.129S7-Atoh1tm3Hzo/J
Cat. No.: CEMM-07250126
Common Name: Math1 flox
These mice possess loxP sites on either side of the coding region of the atonal homolog 1 gene (Atoh1). When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific expression of the gene and elucidating its role in cell fate commitment.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Atoh1tm3Hzo
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| Allele Name |
targeted mutation 3
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Atoh1
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| Gene Name |
atonal bHLH transcription factor 1
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
129S7/SvEvBrd-Hprtb-m2
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| Molecular Note |
A loxP site was inserted 300 bp upstream of the translation start site and a second loxP site was inserted along with an Frt flanked neo cassette immediately 3' of the coding region. The neo cassette was removed by in vivo Flp-mediated recombination leaving the entire coding region flanked with loxP sites.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintained as a live colony, homozygotes may be bred.
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For Research Use Only.
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