Online Inquiry
B6.129(Cg)-Wwtr1tm1Hmc/J
Cat. No.: CEMM-07250926
Common Name: Tazflox
Tazflox floxed mutant mice possess loxP sites flanking exon 2 of the Wwtr1 gene. This strain may be useful for generating conditional mutations in applications related to the Hippo signaling pathway, organogenesis, tumorigenesis, and tumor suppression.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Wwtr1tm1Hmc
show more
close
|
| Allele Name |
targeted mutation 1
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
show more
close
|
| Gene Symbol |
Wwtr1
show more
close
|
| Gene Name |
WW domain containing transcription regulator 1
show more
close
|
| Chromosome |
3
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
show more
close
|
| Molecular Note |
A loxP site was inserted in intron 1 and a loxP site and FRT flanked neo cassette were inserted in intron 2 via homologous recombination.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
show more
close
|
| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
show more
close
|
| Breeding Strategy |
Homozygote x Homozygote
show more
close
|
For Research Use Only.
Related Products