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B6.129-Sncbtm1Sud/J
Cat. No.: CEMM-07250096
Common Name: BSF
These mice possess loxP sites on either side of exon 2 of the targeted gene. Mice that are homozygous for this allele are viable, normal in size and do not display any gross physical or behavioral abnormalities, but breed very poorly. Protein levels are normal. When bred to a strain expressing Cre recombinase, this mutant mouse strain may be useful in studies of presynaptic proteins and synaptic vesicles.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Sncbtm1Sud
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Sncb
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| Gene Name |
synuclein
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| Chromosome |
13
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A targeting vector was designed to flank the first coding exon (exon 2) with loxP sites and to insert an FRT flanked neomycin resistance gene into intron 3. Crossing with mice expressing FLP recombinase excised the neo.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintained as a live colony, homozygotes or heterozygotes may be bred.
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For Research Use Only.
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