Online Inquiry
STOCK Cnih3tm1.1Ran/J
Cat. No.: CEMM-07250668
Common Name: Cnih3fl
The Cnih3fl floxed allele has loxP sites flanking exon 4 of the cornichon-3 gene. Removal of the floxed sequence creates a null allele. These mice may be useful in studying the role of synaptic glutamate AMPA receptors in hippocampal synaptic transmission/plasticity, nociception and behavioral, social and cognitive abnormalities, as well as neuropsychiatric disorders such as schizophrenia and depression/mania.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Cnih3tm1.1Ran
show more
close
|
| Allele Name |
targeted mutation 1.1
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
show more
close
|
| Gene Symbol |
Cnih3
show more
close
|
| Gene Name |
cornichon family AMPA receptor auxiliary protein 3
show more
close
|
| Chromosome |
1
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6NTac x 129S6/SvEvTac)F1
show more
close
|
| Molecular Note |
A loxP site was inserted upstream of exon 4. An FRT and loxP-flanked neomycin resistance cassette was inserted downstream of exon 4. Flp-mediated recombination removed the neomycin resistance cassette.
show more
close
|
| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
show more
close
|
| Breeding Considerations |
When maintaining a live colony, heterozygous mice may be bred together or to wildtype mice from the colony. Alternatively, homozygous mice may be bred together.
show more
close
|
| Breeding Strategy |
Heterozygote x Heterozygote
show more
close
|
For Research Use Only.
Related Products