C57BL/6-Gt(ROSA)26Sortm1(Fabp5)Galf/J

Cat. No.: CEMM-07251079

Common Name: LSL-FABP5
Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.LSL-FABP5 mice have the mouse Fabp5 cDNA and a YFP reporter behind a loxP-flanked STOP cassette. These mice allow for Cre-inducible over-expression of FABP5 protein and YFP in cells/tissues as determined by the Cre promoter and may be useful in the study of immunology and infectious disease.
Inquiry
Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Gt(ROSA)26Sortm1(Fabp5)Galf
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Allele Name
targeted mutation 1
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Allele Attributes
Conditional ready (e.g. floxed); Reporter; Inserted expressed sequence
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Gene Symbol
Gt(ROSA)26Sor
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Gene Name
gene trap ROSA 26
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Chromosome
6
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MGI Accession ID show more close
Strain of Origin
C57BL/6N-Atm1Brd
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Molecular Note
The targeting vector contains from 5' to 3' a loxP site, a STOP cassette containing a neomycin resistance gene followed by a second loxP site, the murine Fabp5 cDNA, a viral 2A oligopeptide (T2A) self cleaving peptide (which mediates ribosomal skipping), and a yellow fluorescent protein (YFP) reporter, and a polyadenylation sequence.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
Both heterozygous and homozygous mice are viable and fertile with normal breeding, and no reported gross phenotypic or behavioral abnormalities. When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony or to C57BL/6J inbred mice.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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