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STOCK Ascl1tm2.1Fgu/JejoJ
Cat. No.: CEMM-07251086
Common Name: Ascl1flox
Ascl1flox/flox mice have loxP sites flanking the entire coding region of the Ascl1 gene and also contain a Venus fluorescent sequence downstream of the floxed region. This mutant mouse strain may be useful in studying distinct neuronal cell populations, neuronal turnover, and neuronal migration. The donating investigator reports that the level of expression of the Venus reporter gene is below detection via direct fluorescence and immunohisotchemistry.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ascl1tm2.1Fgu
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Ascl1
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| Gene Name |
achaete-scute family bHLH transcription factor 1
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| Chromosome |
10
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| MGI Accession ID | show more close |
| Strain of Origin |
Not Specified
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| Molecular Note |
A loxP site was inserted upstream of the coding sequence. A Venus gene with a 5' loxP site and an FRT flanked neo cassette were inserted downstream of the 3' UTR. Flp-mediated recombination removed the selection cassette.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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