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B6.129-Kalrntm2Npl/J
Cat. No.: CEMM-07250869
Common Name: KalSRCKO
KalSRCKO mice possess loxP sites flanking exon 13 of the kalirin, RhoGEF kinase (Kalrn) gene. These mice are useful when studying the role of Kalirin in cardiovascular disease, psychiatric disorders and neurodegeneration.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Kalrntm2Npl
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Kalrn
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| Gene Name |
kalirin
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| Chromosome |
16
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| MGI Accession ID | show more close |
| Strain of Origin |
129
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| Molecular Note |
Exon 13, an exon in the spectrin repeat region (KalSR), was floxed. Flp-mediated recombination removed the neomycin resistance cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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