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B6;129S2-Rapgef3tm1Geno/J
Cat. No.: CEMM-07250399
This strain may be useful for generating conditional mutants for applications related to cognition and social dysfunction. Inserted loxP sites flank exons 3 to 6 of the Rapgef3 (Rap guanine nucleotide exchange factor 3) gene, an intracellular receptor for cyclic AMP.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Rapgef3tm1Geno
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Rapgef3
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| Gene Name |
Rap guanine nucleotide exchange factor (GEF) 3
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| Chromosome |
15
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| MGI Accession ID | show more close |
| Strain of Origin |
129S2/SvPas
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| Molecular Note |
The targeting vector was designed to insert a loxP site upstream of exon 3, followed by an FRT flanked neomycin cassette, and a second loxP site downstream of exon 6. The vector contained a 6.3 kb long homology arm and a 1.6 kb short homology arm.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF1/J
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| Breeding Considerations |
While maintaining a live colony, these mice are bred as homozygotes.
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For Research Use Only.
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