Online Inquiry
B6;129-Gt(ROSA)26Sortm1(Actb-T, -GFP)Dalco/J
Cat. No.: CEMM-07250535
Common Name: floxed STOP-brachury
These floxed stop-brachury mice are suitable for use as a model for chordoma. Until crossed with a cre strain, a floxed stop cassette blocks expression of the chimeric protein.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm1(Actb-T,-GFP)Dalco
show more
close
|
| Allele Name |
targeted mutation 1
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); Inserted expressed sequence; No functional change
show more
close
|
| Gene Symbol |
Gt(ROSA)26Sor
show more
close
|
| Gene Name |
gene trap ROSA 26
show more
close
|
| Chromosome |
6
show more
close
|
| Expressed Genes |
GFP, Green Fluorescent Protein; T, brachyury, T-box transcription factor T, mouse, laboratory
show more
close
|
| MGI Accession ID | show more close |
| Site of Expression |
When combined with Cre recombinase Cre-mediated recombination is observed in a wide variety of tissues.
show more
close
|
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
show more
close
|
| Molecular Note |
A targeting vector containing a floxed STOP cassette followed by murine brachury (T) cDNA and IRES-EGFP under the control of a beta-actin promoter, was inserted into the endogenous Gt(ROSA)26Sor locus.
show more
close
|
| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
show more
close
|
For Research Use Only.
Related Products