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Mouse Models
Site-specific recombinase (SSR) system is widely used in genetically modification, especially the generation for conditional KO and inducible KO mouse models. For making it more efficient and easier, mouse models with special functions have been generated, such as tissue-specifically expressing Cre, inducible expressing Cre, Split-Cre, floxed (target gene were flanked by loxP sites) mouse, et al.
For assisting our global customers making better breakthrough in their research areas, Creative Biogene offers various of mouse models based on site-specific recombinase systems.
- Floxed Mouse: Floxed mouse models provide a way to study gene function in a controlled and tissue-specific manner, allowing researchers to investigate the roles of specific genes in development, physiology, and disease.
- Reporter Mouse: Reporter mouse models generated with SSR technology offer a means to visualize and study gene expression patterns in a tissue-specific or cell-specific manner. They are invaluable tools in deciphering the intricacies of developmental processes and disease mechanisms.
- Inducible Mouse: Inducible mouse models generated with SSR technology are genetically engineered mouse strains that allow for controlled and temporal regulation of gene expression in specific tissues or cell types.
- Recombinase-expressing Mouse: Recombinase-expressing mouse models are genetically modified mouse models that express Cre recombinase tissue-specifically or temporal-specifically.
If you couldn't find the mouse models you need or you are seeking for other model animals, please check out our gene engineering service or just feel free to contact us and get started with our trustable one-stop service.
Our Mouse Models
| C57BL/6-Tg(Nes-cre/Esr1*)1Kuan/J (Cat. No.: CEMM-07250250) | Inquiry | |
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The nestin-CreER transgene contains the rat nestin enhancer/hsp68 minimal promoter directing expression of a tamoxifen-inducible Cre recombinase (Cre-ERT1). When these nestin-CreER transgenic mice are bred with mice containing a loxP-flanked sequence, tamoxifen-inducible Cre-mediated recombination is expected to result in deletion of the floxed sequences in the Cre recombinase-expressing tissues of the offspring. These mice may be useful for studying embryonic and adult neurogenesis.
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| STOCK Tg(Rr5-GFP/cre)1Sapc/J (Cat. No.: CEMM-07250223) | Inquiry | |
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Hoxb4-ENE-GFPCre transgenic mice have expression of a GFP/Cre fusion protein directed primarily to developing spinal cord and hindbrain by the mouse homeobox B4 early neuronal enhancer (ENE) region and heat shock protein 1B minimal promoter. These Hoxb4-ENE-GFPCre transgenic mice may be useful as a Cre-lox or fluorescent tool for the fate-mapping/lineage-tracing of Hoxb4-expressing neurons in the developing neural tube.
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| B6;C3-Tg(Cyp39a1-cre)1Aibs/J (Cat. No.: CEMM-07250133) | Inquiry | |
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These Cyp39a1-Tg1-Cre mice express Cre recombinase under the control of the Cyp39a1 (cytochrome P450, family 39, subfamily a, polypeptide 1) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, hippocampus, striatum, olfactory bulb and cerebellum).
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| B6;C3-Tg(Ctgf-cre)2Aibs/J (Cat. No.: CEMM-07250134) | Inquiry | |
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Ctgf-Tg2-Cre mice express Cre recombinase under the control of the Ctgf (connective tissue growth factor) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex and hippocampus).
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| B6;C3-Tg(Mybpc1-cre)2Aibs/J (Cat. No.: CEMM-07250135) | Inquiry | |
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These 8030451F13Rik-Tg2-Cre (Mybpc1-Cre) express Cre recombinase under the control of the Mybpc1 (myosin binding protein C, slow-type; formerly called 8030451F13Rik) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in the cortex of the brain and hippocampus.
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| B6;C3-Tg(Wfs1-cre/ERT2)3Aibs/J (Cat. No.: CEMM-07250151) | Inquiry | |
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These Wfs1-Tg3-CreERT2 mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Wfs1 (Wolfram syndrome 1 homolog (human)) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, hippocampus, striatum, thalamus and cerebellum).
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| B6;C3-Tg(Scnn1a-cre)1Aibs/J (Cat. No.: CEMM-07250153) | Inquiry | |
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These Scnn1a-Tg1-Cre mice express Cre recombinase under the control of the Scnn1a (sodium channel, nonvoltage-gated 1 alpha) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, striatum, hippocampus and cerebellum).
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| B6;C3-Tg(Scnn1a-cre)2Aibs/J (Cat. No.: CEMM-07250154) | Inquiry | |
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These Scnn1a-Tg2-Cre mice express Cre recombinase under the control of the Scnn1a (sodium channel, nonvoltage-gated 1 alpha) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, thalamus, midbrain and cerebellum).
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| B6;C3-Tg(Cyp39a1-cre)7Aibs/J (Cat. No.: CEMM-07250157) | Inquiry | |
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These Cyp39a1-Tg7-Cre mice express Cre recombinase under the control of the Cyp39a1 (cytochrome P450, family 39, subfamily a, polypeptide 1) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, hippocampus and cerebellum).
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| B6(129S4)-Et(cre/ERT2)4Rdav/J (Cat. No.: CEMM-07250160) | Inquiry | |
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These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.
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For Research Use Only.